Anti-WTAP Antibody [PCRP-BATF3-1E5]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

WTAP

Applications

Flow Cytometry, IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: 1-2 µg/million cells, IHC: 1-2 µg/ml

Molecular weight

14.47 kDa

Light chain

kappa

Clonă

PCRP-BATF3-1E5

Imunogen

Recombinant fragment (around Amino Acids 1-123) of human BATF3 protein (N-terminus).

Specificitate

SNFT, also known as BATF3 (basic leucine zipper transcription factor, ATFlike 3), JUNDM1 or JDP1, is a 127 amino acid protein that localizes to the nucleus and contains one bZIP domain. Interacting with c-Jun, SNFT functions as a negative regulator of AP-1-mediated transcription, specifically by heterodimerizing with c-Jun and binding to DNA response elements. The gene encoding SNFT maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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