Anti-TNFRSF18 Antibody [GITR/1585]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

TNFRSF18

Applications

ELISA

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG3

Molecular weight

25 kDa

Light chain

kappa

Clonă

GITR/1585

Imunogen

full-length human TNFRSF18 protein.

Specificitate

The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.

Storage

Shipped at 4°C. Store at 4°C.

Documentație

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