Anti-TARC / CCL17 Antibody [I11-2A1] (Biotin)

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

TARC/CCL17

Applications

Immunoassay

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Conjugate

Biotin

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Immunoassay: 1 µg/ml

Clonă

I11-2A1

Imunogen

E. coli derived recombinant human full length CCL17 (Ala24-Ser94).

Specificitate

This antibody recognises C-C motif chemokine 17, also known as TARC and SCYA17. CCL17 is a C-C chemokine highly expressed by the thymus and other cell types, including fibroblasts. CCL17 induces and enhances a broad spectrum of immune reactions, including some contact hypersensitivity reactions, allograft rejections, inflammatory bowel disease, atopic dermatitis and atherosclerosis. Therapeutic use of antibodies to neutralize CCL17 can block influx of T cells and ameliorate the impact of various diseases. Upregulation of CCL17 has been reported in breast cancer, and predicts a decrease in overall survival for patients with breast cancer. The biotinylated Mouse anti Human CCL17 antibody, clone I11-2A1 (MCA6181B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL17 antibody, clone I02-2A4 (MCA6180GA) as the capture antibody.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Documentație

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