Anti-smooth muscle Myosin heavy chain 11 Antibody [SM-M10]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Smooth Muscle Myosin Heavy Chain 11

Applications

Flow Cytometry, IF, IHC-P

Reactivity

Human, Bovine, Mouse

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: 0.5-1 µg/million cells, IF: 0.5-1 µg/ml, IHC: 1-2 µg/ml

Molecular weight

205 kDa (MHC-1) / 200 kDa (MHC-2)

Light chain

kappa

Clonă

SM-M10

Imunogen

Crude human uterus extract.

Specificitate

Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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