Anti-Semaphorin 4D Antibody [133-1C6]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Semaphorin 4D

Applications

Flow Cytometry, IF

Reactivity

Human, Baboon

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Isotype

IgM

Recommended dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Molecular weight

50 kDa (monomer)

Cross reactivity

This antibody does not react with Horse.

Light chain

kappa

Clonă

133-1C6

Imunogen

PHA stimulated human peripheral blood lymphocytes.

Specificitate

This antibody recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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