Anti-SARS-CoV Nucleoprotein Antibody [3851]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

SARS-CoV Nucleoprotein

Applications

WB, ELISA 

Reactivity

Viral

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography.

Isotype

IgG2b

Recommended dilutions

ELISA: 1 µg/ml, WB: 1 µg/ml

Protein Length

49

Clonă

3851

Secvență

MSDNGPQSNQRSAPRITFGGPTDSTDNNQNGGRNGARPKQRRPQGLPNN

Imunogen

Recombinant fragment amino acids 1-49 of the SARS nucleoprotein.

Aminoacizi

aa 1 - 49

Specificitate

This antibody recognises nucleoprotein, also known as nucleocapsid protein and Protein N. The nucleoprotein (N) is the most abundant viral protein in SARS-CoV-infected cells. It is one of the four structural proteins essential for viral assembly, alongside the spike (S), envelope (E), and membrane (M) proteins. The nucleoprotein encloses the viral genome; during assembly of the virion, nucleoprotein binds to viral RNA and forms the helical nucleocapsid. It appears to be a multifunctional protein, and plays an important role in enhancing viral transcription and assembly. The N protein of a range of coronaviruses are abundantly expressed and are highly immunogenic, and high concentrations of anti-nucleoprotein IgG antibodies have been detected in patients with SARS. These properties have made the nucleoprotein of SARS-CoV-2 a target of interest for developing a vaccine against COVID-19.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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