Anti-Rotavirus Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

1mL

Țintă

Rotavirus

Applications

IF

Reactivity

Viral

Formulation

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Goat

Clonality

Polyclonal

Product form

Liquid

Concentration

5 mg/ml

Isotype

IgG

Imunogen

Nebraska calf diarrhea virus.

Specificitate

This antibody recognises rotavirus and is specific for ICPs and late structural (virion) antigens. It has been reported to exhibit 90% cross reactivity with human rotavirus and does not react with HEp-2 cells or WI-38 cells in immunofluorescence.Rotavirus is a virus that infects the bowels and is the most common cause of gastroenteritis in infants. 7 major groups have currently been identified, 3 of which infect humans (groups A, B and C). The rotavirus genome consists of 11 segments of double stranded RNA held in the inner core of the three layered, icosahedral virion particle. The genome codes for 6 virus proteins (VP1,2,3,4,6,7) and 6 non-structural proteins (NSP1-6). Outer capsid proteins are VP4 and VP7, inner capsid -VP6 and core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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