Anti-Reticulon 1C Antibody [RNL-4]

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Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

10µg · 100µg

Țintă

Reticulon 1C

Applications

Flow Cytometry, ICC, IHC-Fr, WB

Reactivity

Human, Rat, Porcine

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG1

Clonă

RNL-4

Imunogen

A synthetic peptide encompassing the unique 20 N-terminal amino acid sequence of Reticulon-1C.

Specificitate

This antibody binds an epitope located within the first 20 amino acids of Reticulon-1C (NSP-C). It reacts with peripheral nerves and ganglia of various tissues and cross-reacts with smooth muscle cells and myoepithelium. In the central nervous system, it reacts with the neurohypophysis and pars intermedia of the pituitary gland, and a weak diffuse staining was observed in neurons of the granular and molecular layer of the cerebellar cortex, while glial cells, cerebellar medulla and Purkinje cells are negative. Reticulon-1 has been found to indicate neuronal differentiation and to be downregulated in neurological pathologies.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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