Anti-PRMT7 Antibody [PCRP-PRMT7-1A7]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

PRMT7

Applications

IP, WB, IF, Flow Cytometry

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

IP: 1-2µg / 100-500µg proteins, WB: 1-2 µg/ml, IF: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells

Molecular weight

78.46 kDa

Cross reactivity

This antibody is predicted to cross react with Rat.

Clonă

PCRP-PRMT7-1A7

Imunogen

Recombinant full-length human PRMT7 protein.

Specificitate

Arginine methylation is an irreversible protein modification catalyzed by Arginine methyltransferases, such as PRMT7, which uses S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport and RNA splicing. PRMT7 has two methyltransferase domains, each containing a putative AdoMet-binding motif. The N-terminal methyltransferase domain closely resembles the catalytic core of PRMT5, and the C-terminal domain is most similar to that of PRMT1. Three PRMT7 splice variants have been identified by database analysis. PRMT7 is localized to the nucleus and cytoplasm and moderate expression is observed in adult brain and lung tissues.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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