Anti-Podoplanin / gp36 Antibody [4D5aE5E6]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Podoplanin/gp36

Applications

IHC-P, IHC-Fr

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

IHC-Fr: 0.75 µg/ml - 2 µg/ml

Clonă

4D5aE5E6

Imunogen

ORF human podoplanin ectodomain expressed in E.coli.

Specificitate

This antibody recognises human podoplanin also known as gp36, Aggrus, PA2.26 antigen or T1 alpha. Podoplanin is a 140 amino acid ~36 kDa single pass, type I cell membrane-associated glycoprotein, with a broad spectrum of distribution. Podoplanin is strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver.Podoplanin is preferentially expressed on lymphatic and absent on blood endothelium and therefore Mouse anti Human podoplanin antibody, clone 4D5aE5E6 is readily able to distinguish between lymphatic vessels and blood vasculature. Podoplanin is reported to be a reliable indicator of tumour lymphangiogenesis.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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