Anti-PGP9.5 Antibody [BH7]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µl

Țintă

PGP9.5

Applications

WB, IF 

Reactivity

Human, Mammals, Mouse, Rat, Bovine

Formulation

Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.03% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

IF: 1:500, WB: 1:5,000

Molecular weight

Approximately 24 kDa in rat hippocampal lysate

Clonă

BH7

Imunogen

Recombinant full length human PGP9.5 purified from E.coli.

Specificitate

This antibody recognises protein gene product 9.5 (PGP9.5) also known as ubiquitin C terminal hydrolase 1 (UCH-L1). UCH-L1 is a thiol protease that recognises and hydrolyses a peptide bond at the C-terminal glycine of ubiquitin. This protein is closely related to UCH-L3 and both are thought to recycle ubiquitin to maintain pools of monomeric ubiquitin necessary for proteolysis. UCH-L1 is expressed in neurons and cells of the diffuse neuroendocrine system and their tumours.UCH-L1 and UCH-L3 have been shown to have separate and overlapping functions in the maintanence of neurons of the gracile tract, nucleus tractus solitarius (NTS) and area postrema.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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