Anti-PD1 Antibody [EH12.2H7] (PE)

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100T

Țintă

PD1

Applications

Flow Cytometry

Reactivity

Human, Primate

Formulation

Supplied in Phosphate Buffered Saline with 0.2% BSA and <0.1% Sodium Azide.

Conjugate

PE

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

Lot Specific

Purification

Size exclusion chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Purity

> 95% (by SDS-PAGE).

Clonă

EH12.2H7

Specificitate

This antibody recognises CD279, a co-stimulatory molecule also known as programmed cell death-1 (PD-1).CD279 is a ~50-55 kDa membrane protein which is a member of the CD28 family, and functions as a regulator of T cell activation. It has two specific ligands; CD274 (PD-L1) and CD273 (PD-L2), and their interaction is key in the balance between stimulatory and inhibitory signals needed for effective immune responses to microbes and self-tolerance.CD279 is a marker for germinal center-associated T cells (Dorfman et al, 2006) and is inducibly expressed by T cells, B cells, NKT cells and monocytes upon activation.

Storage

Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light.

Documentație

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