Anti-PAX7 Antibody [PAX7/497]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

PAX7

Applications

IF, Flow Cytometry, WB

Reactivity

Human, Mouse, Rat, Chicken, Zebrafish

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

IF: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml

Molecular weight

57 kDa

Light chain

kappa

Clonă

PAX7/497

Imunogen

Recombinant fragment, around amino acids 301-505, of human PAX7 protein. The exact sequence is proprietary.

Specificitate

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

• Fișă tehnică (PDF)se deschide pe site-ul producătorului