Anti-PAX5 Antibody [PAX5/3735] (Biotin)

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Descriere

Specificații

Brand

Antibodies

Mărime

50µg

Țintă

PAX5

Applications

WB, IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Biotin

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

WB: 2-4 µg/ml, IHC-P: 1-2 µg/ml

Molecular weight

42 kDa

Light chain

lambda

Clonă

PAX5/3735

Imunogen

Recombinant fragment, within amino acids 235-382, of human PAX5 protein. The exact sequence is proprietary.

Specificitate

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 21,000, full-length human proteins. The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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