Anti-PAX4 Antibody [PAX4/7599]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

PAX4

Applications

IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

IHC: 1-2 µg/ml

Molecular weight

38 kDa

Light chain

kappa

Clonă

PAX4/7599

Imunogen

Recombinant fragment (around Amino Acids 1-200) of human PAX4 protein. The exact sequence is proprietary.

Specificitate

Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80% identical to the deduced mouse Pax-4 protein.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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