Anti-Notch1 Antibody [mN1A]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Notch1

Applications

WB, Flow Cytometry, IHC-Fr

Reactivity

Mouse, Human

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

IHC-Fr: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl

Clonă

mN1A

Imunogen

Synthetic peptide corresponding to the cdc10-NCR region within mouse Notch1.

Specificitate

This antibody recognises Notch 1, one of the four major transmembrane receptors (Notch 1-4) of the Notch signaling pathway, which is activated through binding to DSL domain-containing membrane-bound specific ligands.Notch 1 is expressed in a range of cells including haematopoietic cells in mouse foetal liver, adult thymus and bone marrow. Notch 1 signaling plays a role in follicular differentiation, tissue homeostasis, and in both CD4+ and CD8+ cell maturation in the thymus.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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