Anti-Newcastle Disease Virus Antibody [8H2]

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Descriere

Specificații

Brand

Antibodies

Mărime

200µg

Țintă

Newcastle Disease Virus

Applications

ELISA

Reactivity

Viral

Formulation

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Clonă

8H2

Imunogen

Glycoprotein haemagglutinin-neuraminidase of Newcastle Disease Virus (La-Sota strain).

Specificitate

This antibody recognises the hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV). Newcastle disease is a highly contagious disease affecting wild and domestic birds.Symptoms of the disease vary greatly, depending on the strain of virus and the species, age and health of the bird. Virulence of the disease can also vary greatly, with some strains causing very high mortality rates. In humans, NDV can cause mild influenza-like symptoms. The HN protein of the virus is a type II membrane glycoprotein on virion and infected cell surfaces. It binds to sialic acid-containing cellular receptors and promotes activity of the viral fusion protein, thereby allowing the virus to penetrate the cell. It also removes sialic acids from progeny virus particles to prevent viral self-agglutination. Newcastle disease virus is tumor selective and oncolytic. It has shown promise for selective growth in and killing of a variety of tumor cells.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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