Anti-NCR1 Antibody [VIV-KM1] (APC)

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Descriere

Specificații

Brand

Antibodies

Mărime

100T

Țintă

NCR1

Applications

Flow Cytometry

Reactivity

Porcine

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Conjugate

APC

Host

Mouse

Clonality

Monoclonal

Product form

Lyophilized

Concentration

Reconstitution dependent.

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Reconstitution

Reconstitute with 1 ml of distilled water.

Clonă

VIV-KM1

Imunogen

Fusion protein consisting of the extracellular region of porcine CD335.

Specificitate

This antibody recognises the porcine homologue of human CD335, also known as NKp46 and natural cytotoxicity triggering receptor 1 (NCR1), a member of the natural cytotoxicity receptor (NCR) family.CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor and is involved in the control of viral infection and tumor development. CD335 is expressed by human natural killer cells. The development of monoclonal antibodies to bovine CD335 (clone AKS1) and ovine CD335 (clone EC1.1) have enabled researchers to identify and better understand ruminant NK cells. Mouse anti Pig CD335 antibody, clone VIV-KM is the first monoclonal developed to specifically identify porcine CD335 and provides a reagent to facilitate a better understanding of the pig immune system and aid in the understanding of the role of NK cells in host pathogen defense. Porcine CD335 is not expressed by all NK cells and expression may be influenced by cytokine production.

Storage

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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