Anti-NCOA62 / SNW1 Antibody [PCRP-SNW1-1C12]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

NCOA62/SNW1

Applications

Flow Cytometry

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG2a

Recommended dilutions

Flow Cytometry: 1-2 µg/million cells

Molecular weight

61.49 kDa

Cross reactivity

This antibody is predicted to cross react with Chicken, Mouse and Rat.

Clonă

PCRP-SNW1-1C12

Imunogen

Recombinant fragment of human SNW1 protein.

Specificitate

Nuclear receptor coactivator NCOA62/SNW1 (Nuclear Protein SkiP, SKIIP ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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