Anti-NCAM1 Antibody [123C3]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

100µg · 200µg

Țintă

NCAM1

Applications

IHC-P, IHC-Fr, ELISA, Flow Cytometry

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: 1:25 - 1:10 Pack Size: 0.1 mg 1:50 Pack Size: 0.2 mg, IHC-P: 1:100 - 1:200, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Cross reactivity

This antibody does not cross react with Rat.

Clonă

123C3

Imunogen

Membrane preparation of small lung carcinoma.

Specificitate

This antibody recognises human neural cell adhesion molecule (NCAM), otherwise known as CD56. The CD56 molecule is a cell surface glycoprotein expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180 kDa form, while hemopoietic cells express the 140 kDa isoform. recognises both the 140 kDa and the 180 kDa isoform of the CD56 protein.In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumors including tumors of the lung, neural derived malignancies and natural killer cell lymphomas.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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