Anti-Mucin 5AC Antibody [1-13M1]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Mucin 5AC

Applications

WB, IHC-P, ELISA, IHC-Fr

Reactivity

Human

Formulation

Supplied in phosphate-buffered saline with 0.02% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Isotype

IgG1

Clonă

1-13M1

Imunogen

A BALB/c mouse was immunized with mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification).

Specificitate

This antibody recognises the peptide core of gastric mucin, also known as Mucin-5AC, Lewis B blood group antigen, Major airway glycoprotein or Tracheobronchial mucin.Mucins are high molecular weight glycoproteins found predominantly in the secretions of mucus membranes, protecting them from infection or chemical damage. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen. Mouse anti Human Mucin 5AC antibody, clone 1-13M1 has not been cross-adsorbed and may react with related peptides from other species.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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