Anti-Mu Opioid Receptor (phoshpo Thr376) Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

300µl

Țintă

Mu Opioid Receptor

Applications

IHC

Reactivity

Human, Mouse, Rat

Formulation

Supplied in Dulbecco's PBS, pH 7.4, with 150 mM NaCl and 0.005% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Purification

Antigen affinity purification.

Isotype

IgG

Recommended dilutions

IHC: 1:50

Antigen species

Human, Mouse, Rat

Imunogen

Synthetic phosphopeptide derived from human Mu Opioid Receptor around the phosphorylation site of Thr376. Immunogen range is 10-12 amino acids.

Specificitate

This antibody binds specifically to the phosphorylated form of human Mu Opioid Receptor at residue Thr376. It detects phosphorylation induced by high- and low-efficacy agonists, as well as PKC activation, in Western blot analysis. Thr376 phosphorylation is associated with Mu Opioid Receptor desensitization, ß-arrestin recruitment, and tolerance. It supports detection in mouse brain tissue in vivo.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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