Anti-MLL5 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

100µl

Țintă

MLL5

Applications

WB

Reactivity

Human, Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

WB: 1:500-1:2,000

Imunogen

A peptide derived from within human KMT2E.

Specificitate

This antibody recognises lysine methyltransferase 2E, otherwise known as MLL5.KMT2E is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family of proteins, a group of proteins that are homologous to the evolutionary conserved trithorax group crucial for the regulation of homeotic gene (HOX) expression and embryonic development. Aberrant levels of KMT2E have been shown to inhibit cell cycle progression. Mutations in the KMT2E gene have also been associated with neurological disorders such epilepsy and autism as well as abnormalities in gastrointestinal function (O’Donnell-Luria et al. 2019).

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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