Anti-MHC Class II DQ Antibody [2C4]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

MHC Class II DQ

Applications

IP, Flow Cytometry, IHC-Fr

Reactivity

Rabbit

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

Flow Cytometry: 1:25 - 1:200, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood

Clonă

2C4

Imunogen

Rabbit spleen cells.

Specificitate

This antibody recognises the class II RLA-DQ molecule. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In rabbits, this complex is referred to as the rabbit leukocyte antigen (RLA) region. There are 3 major MHC class II proteins encoded by the RLA which are RLA DP, RLA DQ and RLA DR.recognises the RLA DQ molecule, expressed by antigen presenting cells, B cells and monocytes. Mouse anti rabbit MHC class II monoclonal antibody, clone 2C4 is able to significantly inhibit the mixed lymphocyte reaction. Immunoprecipitation with the antibody yields three bands of molecular weights 28, 31 and 35 kDa.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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