Anti-Melanoma Associated Antigen Antibody [NKI-Beteb]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Melanoma Associated Antigen

Applications

IHC-Fr, IHC-P

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG2b

Clonă

NKI-Beteb

Imunogen

A smooth membrane fraction of a lymph node metastasis of melanoma.

Specificitate

This antibody binds Melanoma Associated Antigen, a glycoprotein of 100 + 7 kDa dispersed in the cytoplasma of melanoma cells, and is more concentrated inside vacuoles and sometimes on the melanosomes. Occasionally the antigen is seen on the cell surface. The antigen is actively shed from living cells. The antibody reacts with melanomas, clear cell sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes. Except for one case of non Hodgkin's lymphoma in which macrophages were positive, the antigen has not been detected with other tumors or tissues observed.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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