Anti-Macrophage Inflammatory Protein 3 alpha Antibody [O03-3H12] (Biotin)

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Macrophage Inflammatory Protein 3 alpha

Applications

ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Conjugate

Biotin

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

100 µg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

ELISA: 1 µg/ml.

Clonă

O03-3H12

Imunogen

E. coli derived recombinant human full length CCL20 (Ala27-Met96).

Specificitate

This antibody recognises C-C motif chemokine 20, also known as LARC, MIP3A, and SCYA20. The chemokine CCL20 is expressed mostly in the lymphatic tissue, lung, and liver, and is produced by cells involved with the inflammatory and immune responses. CCL20 plays an important role in recruiting inflammatory cells to the site of infection or injury. However, CCL20 is involved with pathogenesis of chronic inflammatory disorders, specifically interstitial lung fibrosis and chronic obstructive pulmonary disease (COPD), and can contribute to tumor metastasis. Inhibition of CCL20, along with its ligand CCR6, might have valuable therapeutic potential for treatment of autoimmune and inflammatory diseases, and is therefore a target of interest for drug discovery. The biotinylated Mouse anti Human CCL20 antibody, clone O03-3H12 (MCA6203B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL20 antibody, clone J03-4D4 (MCA6202GA) as the capture antibody.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Documentație

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