Anti-LRG1 Antibody [LRG1/4883]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

LRG1

Applications

IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG2c

Recommended dilutions

IHC-P: 1-2 µg/ml

Molecular weight

38 kDa

Light chain

kappa

Clonă

LRG1/4883

Imunogen

Recombinant fragment, around amino acids 30-180, of human LRG1 protein. The exact sequence is proprietary.

Specificitate

LRG1 (leucine-rich α2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains 8 LRR (leucine-rich) repeats and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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