Anti-LMO2 Antibody [LMO2/1971]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

LMO2

Applications

Flow Cytometry, WB, IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG2b

Recommended dilutions

Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml, IF: 1-2 µg/ml

Molecular weight

24 kDa

Light chain

kappa

Clonă

LMO2/1971

Imunogen

Recombinant fragment, around amino acids 23-140, of human LMO2 protein. The exact sequence is proprietary.

Specificitate

The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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