Anti-Lck (phospho Tyr394) Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

50µl

Țintă

Lck

Applications

WB

Reactivity

Human, Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

Lot Specific

Isotype

IgG

Recommended dilutions

WB: 1:500-1:2,000

Imunogen

Phospho-specific peptide corresponding to residues surrounding Tyr394 of human LCK.

Specificitate

This antibody recognises LCK, also known as tyrosine-protein kinase Lck, leukocyte C-terminal Src kinase, lymphocyte cell-specific protein-tyrosine kinase or p56-LCK, when phosphorylated at tyrosine 394. LCK is a member of the Src family of tyrosine kinases. The T cell antigen receptor (TCR) depends on LCK to initiate signaling.LCK is autophosphorylated at tyrosine 394 in response to TCR engagement. Phosphorylation of LCK at tyrosine 394 leads to phosphorylation of CD3 and the gamma chains of the TCR as part of T cell activation.

Storage

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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