Anti-Ku70 Antibody [KU729] - BSA and Azide free

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Ku70

Applications

Flow Cytometry, IF, ICC

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, ICC: 1-2 µg/ml

Molecular weight

70 kDa / 80 kDa

Cross reactivity

This antibody is predicted to cross react with Mouse, Rat, or Chicken.

Light chain

kappa

Clonă

KU729

Imunogen

Nuclear extract of human HL-60 cells.

Specificitate

This antibody recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. This antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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