Anti-KLF17 Antibody [PCRP-KLF17-1G2]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

KLF17

Applications

IP, WB, IF, Flow Cytometry

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG2a

Recommended dilutions

IP: 1-2µg / 100-500µg proteins, WB: 1-2 µg/ml, IF: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells

Molecular weight

43 kDa (predicted) / 57 kDa (observed)

Clonă

PCRP-KLF17-1G2

Imunogen

Recombinant full-length human KLF17 protein.

Specificitate

Kr ppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and which co-regulators they interact with. KLF17 (Kr ppel-like factor 17), whose alternative names include ZNF393 (zinc finger protein 393) or zfp393, is a 389 amino acid nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family. Expressed in testis and ovary, KLF17 may function as a germ cell-specific transcription factor involved in oocyte development and spermatid differentiation. Containing three C2H2-type zinc fingers which bind G/C-rich sites, KLF17 activates transcription from CACCC-box elements.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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