Anti-JAM-C Antibody [CRAM-18 F26] - BSA and Azide free

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

1mg

Țintă

JAM-C

Applications

IHC-Fr, Flow Cytometry, IF, Functional Assays

Reactivity

Mouse, Human

Formulation

Supplied in Phosphate Buffered Saline.

Conjugate

Unconjugated

Host

Rat

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

Flow Cytometry: 1:10 - 1:25, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Clonă

CRAM-18 F26

Imunogen

Recombinant soluble JAM-C.

Specificitate

This antibody recognises mouse and human Junctional adhesion molecule C (JAM-C), also known as JAM-3 and, historically, as JAM-2.JAM-C is expressed at junctions between endothelial and epithelial cells, as well as on leukocytes, platelets, vascular smooth muscle cells and fibroblasts, amongst other cell types. It plays a role in tight junctions and inflammatory processes and interacts with JAM-A and JAM-B.Clone CRAM-18 F26 has been reported to inhibit transendothelial migration (Johnson-Léger et al. 2002).

Storage

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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