Anti-IL-1RA Antibody [IL1RA/4712]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

IL-1ra

Applications

IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG2

Recommended dilutions

IHC: 1-2 µg/ml

Molecular weight

~ 17, 25 kDa

Light chain

lambda

Clonă

IL1RA/4712

Imunogen

Recombinant fragment (around Amino Acids 1-200) of human Interleukin-1RA protein. The exact sequence is proprietary.

Specificitate

Two forms of interleukin-1, designated IL-1a and IL-1 binding to interleukin receptors. By neutralizing the activity of IL-1, IL-1ra contributes to the inhibition of the immune and inflammatory responses and has been targeted as a drug for the treatment of severely active rheumatoid arthritis. There are four isoforms of IL-1ra that are produced as a result of alternative splicing events.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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