Anti-IL-1 beta Antibody - BSA and Azide free

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Descriere

Specificații

Brand

Antibodies

Mărime

500µg

Țintă

IL-1 beta

Applications

ELISA, Functional Assays, WB

Reactivity

Chicken

Formulation

Supplied in Phosphate Buffered Saline.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

500 µg/ml

Isotype

IgG

Molecular weight

Approximately 29 kDa in HD-11 cell lysates transfected with chIL-1.

Imunogen

Recombinant Chicken IL-1 beta.

Specificitate

This antibody recognises chicken Interleukin 1 beta (chIL-1beta), which shares homology with mammalian IL-1beta.IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression.Chicken models indicate physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica.Rabbit anti Chicken interleukin-1 beta antibody (AHP941Z) neutralizes chicken IL-1 beta.

Storage

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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