Anti-Heme Oxygenase 1 Antibody

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Descriere

Specificații

Brand

Antibodies

Mărime

50µg

Țintă

Heme Oxygenase 1

Applications

WB, IHC-Fr

Reactivity

Human, Bovine, Mouse, Rat, Pig

Formulation

Supplied in Phosphate Buffered Saline with 0.065% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG

Recommended dilutions

IHC-Fr: 1:50 - 1:1,000, WB: 1:1,000

Cross reactivity

This antibody does not cross react with Dog.

Protein Length

14

Secvență

HDLSEALKEATKEVHC

Imunogen

Synthetic peptide sequence HDLSEALKEATKEVHC corresponding to amino acids 12-25 (+C-NH2 of human heme oxygenase 1.

Aminoacizi

aa 12 - 25

Specificitate

This antibody recognises human heme oxygenase-1 (HO-1), a 288 amino acid enzyme with a crucial role in heme catabolism, cleaving the heme ring to form biliverdin which is further processed to form bilirubin by a reductase enzyme. HO-1 activity is highest in the spleen where it is involved in the processing of senescent erythrocytes. HO-1 expression can be increased during cellular stress, including heat shock. Baseline levels of expression are high in certain tissues, including spleen and liver. Enriched enzyme preparations are recommended for experimental analysis.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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