Anti-hCG beta Antibody [P1G7F12 (BIO-BCG-005)]

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Descriere

Specificații

Brand

Antibodies

Mărime

1mg

Țintă

HCG beta

Applications

RIA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Clonă

P1G7F12 (BIO-BCG-005)

Imunogen

Human Chorionic Gonadotropin beta subunit from human pregnancy urine.

Specificitate

This antibody recognises the beta subunit of human chorionic gonadotropin (hCG).Minimal cross-reactivity (0.5% ) has been observed with the intact hCG molecule and negligible reactivity has been shown with the human luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH). Human chorionic gonadotropin exists in 5 different variants (hCG, sulfated hCG, hyperglycosylated hCG, free beta hCG and hyperglycosylated free beta) that share the same amino acid sequence but have different functions (Cole 2012). hCG is a glycoprotein of 237 amino acids. Regular hCG has a molecular mass of ~36 kDa where oligosaccharides account for 25-30% of the MW (Cole 2010). hCG is composed of a 92-amino acid alpha subunit, common to the LH, FSH and TSH hormones, and of a unique beta subunit, which is recognized by Mouse anti hCG beta antibody, clone P1G7F12.Production of progesterone is not the only role of hCG: it also has numerous other functions, during pregnancy and as a marker for certain cancers (Cole 2012), (Cole 2010) and (Cole 2009).

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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