Anti-GSTM3 Antibody [rGSTM3/8878] - BSA and Azide free

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

GSTM3

Applications

IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A/G chromatography.

Isotype

IgG2b

Recommended dilutions

IHC: 1-2 µg/ml

Molecular weight

26 kDa

Light chain

kappa

Clonă

rGSTM3/8878

Imunogen

Recombinant full-length human GSTM3 protein.

Specificitate

Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, namely s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. GSTM3 protein is selectively expressed in the testis and brain. GSTM3 may also be tumor suppressive in RCC, as low expression has been demonstrated to correlate with RCC risk and poor prognosis in post-op patients.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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