Anti-Glucose Transporter GLUT4 Antibody [1F8]

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Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

50µg · 100µg

Țintă

Glucose Transporter GLUT4

Applications

WB, IHC-P, IF, IP, IHC-Fr

Reactivity

Rat, Mouse, Monkey, Rabbit, Human, Pig

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Cross reactivity

This antibody does not cross react with Dog.

Clonă

1F8

Imunogen

Partially purified vesicles containing insulin-responsive glucose transporter 4.

Specificitate

This antibody recognises an epitope in the cytoplasmic region of Glucose transporter 4 (GLUT4), an insulin-regulated facilitative glucose transporter found in adipose tissue and striated muscle. When stimulated by insulin, GLUT4 translocates from intracellular stores to the cell surface, facilitating passive diffusion of circulating glucose into muscle and fat cells. GLUT4 is also stimulated to locate to the cell surface by muscle contraction, particularly in cardiac muscle. Mouse anti glucose transporter 4 antibody, clone 1F8 has been used successfully to demonstrate the localization of GLUT4 to the basolateral side of ductal structures in the rat submandibular salivary gland in formalin fixed, paraffin embedded material.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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