Anti-GLIS3 Antibody [PCRP-GLIS3-1B11]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

GLIS3

Applications

ELISA, Flow Cytometry, IP

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: 1-2 µg/million cells, IP: 1-2µg / 100-500µg proteins

Molecular weight

84 kDa

Light chain

kappa

Clonă

PCRP-GLIS3-1B11

Imunogen

Recombinant full-length human GLIS3 protein.

Specificitate

GLIS3 is a member of the GLI similar zinc finger protein family, and encodes a nuclear protein with five C2H2 type zinc finger domains. It functions as both an activator and repressor of transcription, and is specifically involved in the development of pancreatic beta cells, thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full length nature of only two have been determined.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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