Anti-DBC-1 Antibody [PCRP-KIAA1967-1D10]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

DBC-1

Applications

Flow Cytometry, IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG2a

Recommended dilutions

Flow Cytometry: 1-2 µg/million cells, IHC: 1-2 µg/ml

Molecular weight

102.9 kDa

Clonă

PCRP-KIAA1967-1D10

Imunogen

Recombinant full-length human CCAR2 / KIAA1967 protein.

Specificitate

DBC-1 (deleted in breast cancer gene 1 protein), also known as p30 DBC protein, is one of the genes located within the region of chromosome 8p21.3 that is homozygously deleted in some breast cancers. DBC-1 contains a nuclear localization signal, an N-terminal leucine zipper, an EF hand and a C-terminal coiled-coil region. DBC-1 is closely related to DIS but lacks the SAP domain. During death signaling mediated by TNF, stabilizing its expression and therefore collaborating to suppress apoptosis and promote hormone-independent cell growth.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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