Anti-Complement Factor B Antibody [014III-33.2.4.3]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µl

Țintă

Complement Factor B

Applications

Flow Cytometry, ELISA, IHC-Fr, WB, Functional Assays

Reactivity

Human

Formulation

Supplied in Borate Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

Lot Specific

Purification

Protein A affinity chromatography of ascites.

Isotype

IgG1

Clonă

014III-33.2.4.3

Imunogen

Purified human complement factor b.

Specificitate

This antibody recognises the 30 kDa Ba fragment of 90 kDa human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kDa Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Mouse anti Human Complement Factor B (Ba Fragment) antibody, clone 014III-33.2.4.3 blocks activity of the target protein. Removal of Sodium Azide is recommended prior to use in functional assays.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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