Anti-CLEC10A Antibody [ER-MP23]

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Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

25µg · 250µg

Țintă

CLEC10A

Applications

IHC-P, Flow Cytometry, IHC-Fr, IF

Reactivity

Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Rat

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

Flow Cytometry: 1:100 - 1:200, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Clonă

ER-MP23

Imunogen

BALB/c macrophage precursor cell hybrids.

Specificitate

This antibody recognises mouse CD301, a ~38 kDa cell surface protein, otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR).In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.Rat anti Mouse CD301 antibody, clone ER-MP23 is reported to block the function of mouse CD301. Rat anti Mouse CD301 antibody, clone ER-MP23 binds both MGL1 and MGL2 homologues.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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