Anti-CD68 Antibody [KP1 + C68/684]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

CD68

Applications

IHC-P

Reactivity

Human, Monkey, Mouse, Rat, Feline

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Oligoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1, kappa + IgG1, kappa

Recommended dilutions

IHC-P: 1-2 µg/ml

Molecular weight

110 kDa

Clonă

KP1 + C68/684

Imunogen

Clone KP1: Subcellular fraction of human alveolar macrophages. Clone C68/684: Recombinant human CD68 protein.

Specificitate

This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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