Anti-CD46 Antibody [MEM-258] (PE)

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Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

25T · 100T

Țintă

CD46

Applications

Flow Cytometry

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Conjugate

PE

Host

Mouse

Clonality

Monoclonal

Product form

Lyophilized

Concentration

Reconstitution dependent.

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ or 100µl whole blood.

Reconstitution

Pack Size of 25 Tests/0.25ml: Reconstitute with 0.25 ml of distilled water. Pack Size of 100 Tests: Reconstitute with 1 ml of distilled water

Clonă

MEM-258

Imunogen

HPB-ALL cell line.

Specificitate

This antibody recognises the human CD46 cell surface antigen, also known as membrane co-factor protein (MCP), Trophoblast leukocyte common antigen or TLX. CD46 is a 392 amino acid (including a 34 aa signal peptide) ~43-60 kDa single pass type 1 transmembrane glysoprotein expressed by all cell types with the exception of erythrocytes.CD46 functions as areceptor for complement and inhibitor of complement activation, limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilisation.

Storage

Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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