Anti-CD45RB Antibody [MEM-143]

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Descriere

Specificații

Brand

Antibodies

Mărimi disponibile

10µg · 100µg

Țintă

CD45RB

Applications

Flow Cytometry, IHC-P

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A chromatography.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: 0.5-4 µg/ml. The staining pattern of the MEM-143 shows prominent differences from other anti-CD45RB reagents including standard antibody MEM-55, mostly as a result of the recognition of differences in glycosylation, IHC-P: 10 µg/ml; Positive Control: human tonsil.

Antigen species

Human

Clonă

MEM-143

Imunogen

Human peripheral blood lymphocytes.

Specificitate

This antibody reacts with a protein determinant of CD45RB, a 180-240 kDa single chain type I membrane glycoprotein, variant of CD45 (CD45RB isoform). CD45RB is expressed on a subset of T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells. The MEM-143 is therefore not neuraminidase sensitive like most other anti-CD45RB antibodies (including standard antibody MEM-55). The reactivity of the antibody MEM-143 can be blocked by a peptide including amino acids 79-88.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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