Anti-CD44 Antibody [YKIX337.8.7]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

CD44

Applications

Flow Cytometry, IHC-Fr

Reactivity

Canine, Raccoon

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Rat

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

Flow Cytometry: 1:10 - 1:20, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Clonă

YKIX337.8.7

Imunogen

Concanavilin A activated Canine T cells.

Specificitate

This antibody recognises canine CD44, also known as H-CAM, a single-pass type 1 membrane of approximately 90 kDa expressed by most leucocytes and epithelial cells. CD44 expression is markedly increased upon cell activation. CD44 is involved in cell-cell, cell adhesion and cell migration and is the principal cellular receptor for hyaluronate via it's LINK domain, additionally CD44 interacts with other ligands including collagens and metalloproteinases. Altered CD44 expression is detected in many forms of invasive and metastatic cancer, CD44 expression has been observed on canine mammary and melanocytic tumors.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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