Anti-CD32 Antibody [AT10]

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Descriere

Specificații

Brand

Antibodies

Mărime

500µg

Țintă

CD32

Applications

IP, Flow Cytometry, IHC-Fr, Functional Assays

Reactivity

Human, Dog, Rhesus Monkey, Pig

Formulation

Supplied in Phosphate Buffered Saline.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: 20 µg/ml, IHC-Fr 2: 1:500 - 1:1,000, IP: 20 µg/ml, Use 10µl of the suggested working dilution to label 10⁶ cells or cells or 100µl whole blood

Clonă

AT10

Imunogen

K562 cell line.

Specificitate

This antibody recognises the human CD32 antigen, a ~40 kDa glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). CD32 mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Mouse anti Human CD32 antibody, clone AT10 blocks the binding of IgG to Fc gamma RII.

Storage

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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