Anti-CD16 Antibody [AT154-2]

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Descriere

Specificații

Brand

Antibodies

Mărime

250µg

Țintă

CD16

Applications

Flow Cytometry, IHC-Fr

Reactivity

Mouse

Formulation

Supplied in TRIS Buffered Saline with <0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Rat

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG2b

Recommended dilutions

Flow Cytometry: 1:10, IHC-Fr: 1:100 - 1:1,000, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl

Clonă

AT154-2

Imunogen

HEK293F cell expressing CD16 and gamma chain.

Specificitate

This antibody recognises CD16, also known as FcRIII. CD16 is a low affiniity activatory receptor which interacts preferentially with mouse IgG1, IgG2a and IgG2b immune complexes and is involved in various effector functions including phagocytosis, NK antibody dependent cellular cytotoxicity and the release of inflammatory mediators.In mice, CD16 is expressed on macrophages, NK cells, granulocytes, myeloid precursors and subpopulations of T lymphocytes.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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