Anti-CD13 Antibody [WM15] (PE)

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Descriere

Specificații

Brand

Antibodies

Mărime

100T

Țintă

CD13

Applications

Flow Cytometry

Reactivity

Human, Rhesus Monkey

Formulation

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Conjugate

PE

Host

Mouse

Clonality

Monoclonal

Product form

Lyophilized

Concentration

Reconstitution dependent.

Purification

Protein A affinity chromatography of tissue culture supernatant.

Isotype

IgG1

Recommended dilutions

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood

Reconstitution

Reconstitute with 1 ml of distilled water.

Clonă

WM15

Imunogen

Human AML cells.

Specificitate

This antibody recognises human CD13 also known as aminopeptidase N. CD13 is a single pass type II glycosylated integral membrane protein with a predicted molecular mass of ~110 kDa and an apparent molecular mass of ~150 kDa expressed by granulocytes, monocytes, fibroblasts, endothelial cells and by myeloid leukaemia cells. CD13 acts as a major cell surface receptor for group 1 coronoviruses which bind to a critical sequence encompassing amino acid residies 288-295. CD13 functions as an aminopeptidase enzyme, a metalloprotease present as both a membrane bound form and also a soluble aminopeptidase N. Mouse anti Human CD13, clone WM15 inhibits infection of cells by human coronavirus but not hepatitis C virus and inhibits aminopeptidase N activity of the CD13 molecule.

Storage

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

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