Anti-CD11c Antibody [BAQ153A]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

CD11c

Applications

Flow Cytometry, ICC

Reactivity

Bovine, Goat, Sheep, Bison, Water Buffalo

Formulation

Supplied in serum free tissue culture medium containing proprietary protein free supplement and 0.09% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

0.2µM sterile filtered.

Isotype

IgM

Recommended dilutions

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Clonă

BAQ153A

Imunogen

Cells from multiple species.

Specificitate

This antibody recognises bovine CD11c also known as integrin alpha X. CD11c is a receptor for fibrinogen recognizing the G-P-R motif in fibrinogen. It is involved in the cell to cell interaction during inflammatory responses. In addition, it has an important function in adhesion and chemotaxis in monocytes, macrophages and dendritic cells (DCs).In cattle, CD11c+ DCs are a source of the anti-inflammatory cytokine IL-10 during infection by the highly pathogenic foot-and-mouth disease virus (FMDV). IL-10 may be responsible for the reduction in the antigen processing ability of DCs during FMDV infection. Clone BAQ153A reacts with bovine CD11c+ macrophages, DCs and some lymphocytes as shown by IHC and flow cytometry.

Storage

Store at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

• Fișă tehnică (PDF)se deschide pe site-ul producătorului